The well water, or tap water might contain high amount of iron. If it does, then it could the root of your problems.
High iron intake raises histamine in the plasma. High iron intake lowers the other minerals and vitamins. Arthritis, allergies, anger, anxiety, depression, schizophrenia, bipolar, plus others, can be a result of high iron consumption.
The only safe way to get rid of the iron, is low iron diet. It could take 1 - 3 years.